CRANAD 2( —— )

Catalog No. M23364 CAS No. 1193447-34-5

CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

CRANAD 2
Note

Research use only, not for human use.
Brief Description

CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?
Description

CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

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Indication

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Chemical Information

CAS Number

1193447-34-5
Formula Weight

410.26
Molecular Formula

C23H25BF2N2O2
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

CN(C)C1=CC=C(/C=C/C2=[O+][B-](F)(F)OC(/C=C/C3=CC=C(N(C)C)C=C3)=C2)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jara-Guajardo P , Cabrera P , Celis F , et al. Gold Nanoparticles Mediate Improved Detection of β-amyloid Aggregates by Fluorescence[J]. Nanomaterials, 2020, 10(4).

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