CRANAD 2

CAS No. 1193447-34-5

CRANAD 2 ( —— )

Catalog No. M23364 CAS No. 1193447-34-5

CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CRANAD 2
  • Note
    Research use only, not for human use.
  • Brief Description
    CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?
  • Description
    CRANAD-2 is a difluoroboron-derivatized curcumins as near-infrared probe for in vivo detection of amyloid-beta deposits.?Upon interacting with Abeta aggregates, CRANAD-2 undergoes a range of changes, which include a 70-fold fluorescence intensity increase, a 90 nm blue shift (from 805 to 715 nm), and a large increase in quantum yield.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1193447-34-5
  • Formula Weight
    410.3
  • Molecular Formula
    C23H25BF2N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    CN(C)C1=CC=C(/C=C/C2=[O+][B-](F)(F)OC(/C=C/C3=CC=C(N(C)C)C=C3)=C2)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jara-Guajardo P , Cabrera P , Celis F , et al. Gold Nanoparticles Mediate Improved Detection of β-amyloid Aggregates by Fluorescence[J]. Nanomaterials, 2020, 10(4).
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